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Guo YJ, Ni Y, Raman H, Wilson BAL, Ash GJ, Wang AS, Li GD

Furthermore, as shown in Figure 1C, the important upstream side of the known M pro cleavage site at the nsp13/14 junction, NVATLQ/A, is remarkably similar to that of the active site sequence of GPx1, NVASLU/G, where the selenocysteine (U) lines up with a glutamine (Q) in the viral sequence

Understanding these potential mechanisms helps clinicians counsel patients appropriately and distinguish between expected treatment effects and concerning adverse reactions