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Intracellular G-protein-coupled receptors, particularly the trace amine-associated receptor 1 (TAAR1), function as internal sensors of cytoplasmic catecholamines and their metabolites (Underhill et al., 2021)

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Recently, we reported that Syn functions as histone chaperone, binds with high-affinity and specificity to assembled histone H2a-H2b dimer and H3-H4 tetramer 73

Discussion In a crowded cellular environment, protein-protein interactions are influenced not only by binding affinity but also by intracellular concentrations and competition from other proteins 36,52,63,64

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