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For protocols calling for a single use or a preservative-free solvent, sterile water is the alternative

PubMed, Min, Hong Ki, et al

Available in injectable and topical formulations depending on treatment goals

Adjust protocol based on progress Expected timeline: Week 2 to 3: Reduced gut inflammation symptoms (bloating, cramping) Week 4 to 6: Improved tolerance to some previously reactive foods Week 8 to 12: Broader food tolerance, reduced systemic inflammation This protocol works best combined with an elimination diet and careful food reintroduction

The problem with prolonged caloric deficit is that metabolic adaptation your body downregulates energy expenditure over time to resist the deficit