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Mitochondrial Respiration Stress-Protective Hypoxia Effects DSIP has been shown to exert direct effects on brain mitochondrial respiration significantly increasing ADP-stimulated (state 3) mitochondrial respiration activity under conditions of experimental hypoxia

This may help explain why retatrutide is being studied for both obesity and type 2 diabetes

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But palpitations accompanied by dizziness, chest pain, shortness of breath, or fainting require immediate medical evaluation to rule out arrhythmias