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GH is produced by the pituitary gland, which is under the positive control of the hypothalamic peptide GH-releasing hormone (GHRH) and the negative feedback of somatostatin

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413 Partial ablation of astrocytes in the prefrontal cortex of healthy rats (by injection of gliotoxin L--aminoadipic acid) resulted in the development of depressive-like behaviours, whereas injection of neurotoxin ibotenate did not have such an effect

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