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Systemic ozone therapy has been proved to be effective to modulate immune system by inducing the production of cytokines from blood mononuclear cells (18,19), and to regulate the oxidative stress by inducing an increase of cellular antioxidant system (20-22)

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For researchers comparing blend versus separate vials, the math is meaningfully close, with the blend earning its small premium through ratio consistency, documentation simplification (one batch, one COA), and single-reconstitution efficiency