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In addition, all related variables in this experiment, like ROS production in PBMC and enzyme activity of superoxide dismutase and glutathione peroxidase ( The present study showed a balanced distribution of carnitine and -butyrobetaine between blood cells and plasma of dairy cows during dietary L-carnitine supplementation, independent of transcriptional regulation of the transporter gene SLC22A5, indicating sufficient baseline transport capacity in PBMCs

Mol Neurobiol 26:1319

The dosing schedule is gradual to minimise side effects, similar to other GLP-1 medications