Practical access strategies For patients in markets where both peptides are available, tirzepatide is the practical choice due to established availability, known dosing protocols, extensive clinical experience, and insurance coverage pathways
Whether you are using brand-name Mounjaro, Zepbound, or compounded tirzepatide from a pharmacy, the dosage principles remain the same
People with inflammatory arthritis often have comorbidities, including heart disease, renal insufficiency, and diabetes, says Dr
Patients are ONLY candidates with a BMI of 25 or above, as that is the indication for overweight
GLP-1 Receptor Agonists (e.g., semaglutide, liraglutide) Increase insulin secretion in response to food Reduce glucagon release (which lowers blood sugar) Slows gastric emptying (which helps with post-meal glucose excursions) Reduces appetite and induces satiety which leads to weight loss GLP-1/GIP Receptor Agonists (e.g., tirzepatide) GLP-1 effects (same as above) GIP effect: further enhances insulin secretion Both medications help with blood sugar control and weight loss, but Mounjaros dual mechanism may offer stronger effects on insulin secretion, which improves A1c levels
