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A C20 fatty diacid moiety, attached at position 17 via a gamma-glutamic acid and aminoethoxyethoxyacetic acid (AEEA) linker, extends the peptides half-life by promoting albumin binding, which slows clearance from the body

The result has been shortages of the drug for diabetics who rely on it to lower their blood sugar, while doctors are also concerned it could be abused by those with eating disorders or others hoping for short-term weight loss