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Natural Remedies for Acid Reflux: Supplement Alternatives Many people seek natural remedies for acid reflux as gentler alternatives to conventional medications

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In addition, in rat brain, the activities of succinate dehydrogenase (Kugler et al., 1988) and NAD + -dependent IDH3 (Patel, 1977), a rate-limiting step of the citric acid cycle (Chen and Ding, 2023), were also shown to decline with aging (Haripriya et al., 2004), which, together with the loss of ACO2 activity, may be major driving forces behind this oxidizing shift in the neuronal mitochondrial [NAD + ]/[NADH] with aging