The newer cholesterol-lowering medications, PCSK9 inhibitors, have been shown to lower Lp(a) levels.[ref] A 2026 placebo-controlled clinical trial using the PCSK9 inhibitor enlicitide also showed a decreased in Lp(a) levels at 24 weeks.[ref] Aspirin: A study of over 12,000 people over age 70 looked at the effect of 100mg of aspirin daily
Theyre common to young and old, as well as healthy individuals
[DOI] [PMC free article] [PubMed] [Google Scholar] Moon C, Marion M, Thanos PK, Steiner H (2021) Fluoxetine potentiates oral methylphenidate-induced gene regulation in the rat striatum
In some cases, improving lifestyle factors or optimizing treatment combinations may enhance responsiveness
Combine with precursors: Nutrients like Nacetylcysteine (NAC) provide cysteine, a building block your body needs to synthesise glutathione efficiently