In the KininKallikrein system, factor XII converts Prekallikrein to Kallikrein and subsequently Kallikrein converts Kininogen to Bradykinin (bradykinin is a vasodilator)
Other ingredients Water, propanediol, butylene glycol, pentylene glycol, niacinamide, glycerin, hydroxyacetophenone, arginine carbomer, ammonium acryloyl dimethyltaurate/vp copolymer, panthenol, ethylhexylglycerin, poluglyceryl 10 laurate, adenosine, dipotassium glycyrrhizate, glutathione, coptis japonica root extract, melia azadirachta flower extract, coccinia indica fruit extract, 1,2-hexanediol, melia azadirachta leaf extract, solanum melongena (eggplant) fruit extract, sodium hyaluronate, ascorbic acid, aloe barbadensis flower extract, corallina officinalis extract, curcuma longa (turmeric) root extract, ocimum sanctum leaf extract, hydroxypropyltrimonium hyaluronate, tocopherol, centella asiatica extract, sodium acetylated hyaluronate, hydrolyzed hyaluronic acid, hyaluronic acid, hydrolyzed sodium hyaluronate, sodium hyaluronate crosspolymer, potassium hyaluronate
The connection is indirect but biologically meaningful
Not generalizable
doi: 10.1210/jc.2011-2614
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