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Clinical research demonstrated that AOD-9604 had no effect on serum IGF-1 levels, confirming that the peptide fragment does not activate the traditional growth hormone receptor pathway

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[12] The benefit was associated with an anti-inflammatory effect together with increased numbers of OPCs and mature oligodendrocytes in the CNS, with BrdU labeling indicating that the peptide stimulated OPC proliferation and their maturation into myelinating cells