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Moderate to Severe Deficiency: For moderate to severe deficiencies, the dosage may increase to 1,000 mcg several times a week initially, followed by a maintenance dose

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Beyond the established roles of short-chain fatty acids (SCFAs) and bile acids, recent findings reveal that branched-chain amino acids, trimethylamine N-oxide, tryptophan and indole derivatives, have been implicated in the pathogenesis of metabolic disorders ( 2.2 Immunomodulatory coordination The gut microbiota plays a crucial role in maintaining immune homeostasis

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Figure 4 Table 4 NAPQI-cysteine diagnostic fragment ions (MS2) detected in HRMS/MS experiments