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Their study found that NRF2 translocation into the nucleus and NAD(P)H quinone oxidoreductase (NQO1) activity were significantly increased after treatment of astrocytes with tert-butylhydroquinone (tBHQ), resveratrol, or curcumin at 2050 M [159]

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These techniques are widely used in metabolite analysis of plasma, urine, and tissue samples, and also play an important role in biomarker discovery

Samples were then incubated overnight with anti- smooth muscle actin (Abcam, MA, United States

The sinister combination of high levels of pro-fibrotic factors such as TGF- and CTGF in osteoarthritic joints with short- and long-term pathologically high mechanical forces facilitate the differentiation of FLS into myofibroblasts a hallmark of OA (149152)