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Dysregulation of this process can result in either loss of specific cell types or over-proliferation, which could lead to a number of human diseases, including cancers (Vermeulen et al., 2003)

This ionization increased with an increase of pH value

This imbalance leads to downregulation of tight junction protein expression, increased intestinal mucosal permeability, and the initiation and exacerbation of inflammatory cascades

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