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However, to date, no biological marker exists to "diagnose" ASD

Urology (2000) 4

This case implies that the melanosis pigment-laden macrophages formed in the lamina propria of the colon pass to the regional lymph nodes and may explain the observation of similar pigment-laden macrophages in other sites

In fact, some therapies can trigger a host of unpleasant side effects, including nausea