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Simultaneously, this decreasing pool of alive cells keeps secreting glutathione until, after ~300 h, the probability of replicating is very close to the probability of dying and very few alive cells are left in the population

The anti-diabetic drug Metformin inhibits vascular endothelial growth factor expression via the mammalian target of Rapamycin complex 1/hypoxia-inducible factor-1 signaling pathway in ELT-3 cells

In addition to increasing the generation of superoxide anions, hydrogen peroxide, and other peroxides, homocysteine may thus decrease the cellular ability to detoxify peroxides, especially hydrogen peroxide

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