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By effectively addressing obesity-linked OSA for many (it reversed the condition in up to 50.2% of SURMOUNT-OSA trial participants), GLP-1s prescribed by primary care physicians and other specialists are clearing the decks, allowing sleep specialists to refocus on the patients whose condition is driven by other factors
Since both diabetes and obesity are risk factors for PDAC, there is a potential role for the use of glucagon-like peptide-1 receptor agonists (GLP-1RAs) for PDAC risk reduction
However, long-term daily use should be discussed with a healthcare professional, especially for people who are pregnant, breastfeeding, taking blood pressure medication or using stimulant medications
Semaglutide at maximum dose produces an intervention magnitude of approximately 1,300 kcal per day, with an expected plateau timeline of around 24 months
2019;6:CD011265
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