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Clin Nutr ESPEN 37: 9-23 Askarpour M et al

The semaglutide versus tirzepatide comparison covers clinical differences in detail

Serious side effects are rare but include pancreatitis (abdominal pain), severe dehydration, and gallbladder issues

The clinical use track record in Eastern Europe and Asia provides a level of real-world safety and efficacy data that purely preclinical peptides lack, though large-scale randomized controlled trials specifically for peripheral neuropathy are still needed

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