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HER2 positive tumors, which comprise ~ 15% of all breast cancers, express high levels of HER2 but lack ER, and PR expression [3,4,5]

This is a critically important strategy to reduce the burden of tobacco use because a recent report estimated that raising the minimum age for purchase of all tobacco products to 21, nationwide, could prevent 223,000 deaths among people born between 2000 and 2019, including 50,000 fewer deaths from lung cancer (60)