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(2018) found that elevated cerebrospinal fluid (CSF) TMAO is associated with biomarkers of AD pathology (phosphorylated tau and phosphorylated tau/A) and neuronal degeneration (total tau and neurofilament light chain protein)
Another study published in 2024 by Vleminckx et al
LC protects the thiol groups of proteins against oxidative action of H 2 O 2 and free radicals (i.e., any molecular species capable of independent existence that contain an unpaired electron in an atomic orbital) and decreases peroxidative damage of the unsaturated fatty acids (FAs) built into membrane phospholipids that stabilize cell membranes and ion canals [9]
Our team occasionally recommended carnitine for people on valproic acid/Depakote, to help with residual side effects like muscle weakness and constipation
An old drug repurposed
