10 weeks on semaglutide 10kgs in 10 weeks. :

Leading telehealth company Hims added generic liraglutide to its lineup last month, joining over a dozen competitors already offering the product in compounded, generic, or name-brand forms

This means waiting roughly two weeks between the last dose of tirzepatide and the first dose of semaglutide

You need to experience the full effect of each dose before deciding whether escalation is appropriate

Appraisal of CagriSema for treatment of obesity and type 2 diabetes 1.Advantages of CagriSema Available data suggest that the HbA1c-lowering efficacy of the combination of cagrilintide and semaglutide was higher than that achieved by each drug alone (table 1) [10]

Tirzepatide may be considered when insulin resistance is a major factor because it targets both GIP and GLP-1 pathways