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Sore throat is a common symptom in the general population , often caused by viral infections, bacterial pharyngitis, or environmental factors

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This interaction leads to mRNA degradation or repression, forming a sophisticated regulatory network that is vital for proper cellular function and development, and is often implicated in various diseases (Figure 3) (Tabnak et al., 2021b

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Microbial metabolites such as SCFAs, including acetate, propionate, and butyrate, are produced by gut bacteria from dietary fiber, essential for maintaining communication between the gut and the brain [259,260,261]